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Corel Medical Series: Cancer
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Corel Medical Series: Cancer.iso
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p08.dxr
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00056_Field_SRC.p08.A.6.txt
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1997-01-28
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• Adoptive This strategy involves transferring immunological cells or molecules that carry information (especially
lymphokines, the cytokines secreted by lymphocytes) that will help the immune system do its work in a more
coordinated way.
• Restorative Cancer itself and treatments like radiation and chemotherapy can decrease the number of
immunological cells available to take part in the immune response. The restorative strategy involves replacing
these cells or accomplishing the same goal indirectly by inhibiting the action of suppressive influences on the
immune system, such as suppressor T cells.
• Passive This strategy involves giving the immune system specific "weapons" such as antibodies or short-lived
antitumor "factors," that can attack specific cells. Special kinds of antibodies can also be programmed to deliver
killer molecules such as radioactive isotopes or toxins to tumor cells.
• Tumor cell modulation This category isn't formally recognized yet, but "tumor cell-modulating
immunotherapy" is really the most appropriate term when talking about biological agents such as the
interferons . All types of immunotherapy depend on the immune cells recognizing the tumor cells. The only
way they can do this is by spotting certain antigens on the surface of these cells, which is not always an easy
thing to do. "Cell modulation" means that the tumor-associated antigens are highlighted, giving the immune cells
a cleaner target to aim for.